EP is a web-resource developed to enable access to neutral evolutionary probabilities (EP) of each possible amino acid residue at a given human protein position (Liu et al., 2016). This evolutionary information can be used to identify single nucleotide polymorphisms (SNPs) with a greater likelihood of functional impact (low EP) or a greater likelihood of neutrality (high EP).
A Molecular Evolutionary Reference for the Human Variome
Molecular Biology and Evolution, 33:245-254
Liu L, Tamura K, Sanderford M, Gray VE, Kumar S